Moustapha Kassem publications

LIST OF PUBLICATIONS

THESES:

1994      PhD thesis (University of Aarhus, Denmark): Human bone cell proliferation and differenti­ation: effects of growth hormone and sex steroids on osteoblasts in vitro.

1997      DSc thesis (University of Aarhus, Denmark): Cellular and Molecular effects of growth hormone and estrogen on human bone cells

PUBLICATIONS:

Original papers  182

Invited reviews/book chapters 67

H-factor: 54, citation number > 11000

Original papers

  1. M.Kassem, R.Okazaki, S.A.Harris,T.C.Spelsberg, C.A.Conover, B.L.Riggs (1996). Potential mechanism of estrogen-mediated decrease in bone formation: estrogen increases production of inhibitory insulin-like growth factor-binding protein-4 in a human osteoblastic cell line with high levels of estrogen receptors. Proc Assoc Amer Physcian 108:2.
  1. M.Kassem, L.Ankersen, E.F.Eriksen, B.F.C.Clark, S.I.S.Rattan (1997). Demonstra­tion of cellular aging and senescence in human osteoblast cultures established from normal and osteoporotic bone. Osteop Int 7:514.
  1. E.F.Eriksen, B.Langdahl, J.Rungby, M.Kassem (1999) Hormone replacement therapy prevents osteoclastic hyperactivity in early menopasue: a histomorphometric study in early postmenopausal women J Bone Miner Res 14:1217.

*52. J. Simonsen, C.Rosada, N.Sernici, J. Justesen, K.Stenderup, S.Rattan, T.Jensen, M.Kassem (2002). Telomerase expression extends lifespan and prevents senescence-associated impairment of osteoblast functions. Nature Biotechnology 20:592

*57. K.Stenderup, J.Justesen, C.Clausen, M.Kassem (2003). Aging is associated with decreased maximal life span and accelerated senescence of bone marrow stromal cells Bone 33:919

*61. Abdallah BM, Jensen CH, Gutierrez G, Leslie RG, Jensen TG, Kassem M (2004) Regulation of human skeletal stem cells differentiation by Dlk1/Pref-1. J Bone Miner Res. 19:841

*65. Serakinci N, Guldberg P, Burns JS, Abdallah B, Schrodder H, Jensen T, Kassem M (2004). Adult human mesenchymal stem cell as a target for neoplastic transformation. Oncogene. 23:5095

*68. Burns JS, Abdallah BM, Guldberg P, Rygaard J, Schroder HD, Kassem M (2005). Tumorigenic heterogeneity in cancer stem cells evolved from long-term cultures of telomerase-immortalized human mesenchymal stem cells. Cancer Res. 65:3126

*70. Kratchmarova I, Blagoev B, Haack-Sorensen M, Kassem M, Mann M (2005) Mechanisms of divergent growth factor effects in mesenchymal stem cell differentiation. Science 308:1472

  1. Qiu W, Andersen TE, Bollerslev J, Mandrup S, Abdallah BM, Kassem M (2007) Patients with High Bone Mass Phenotype Exhibit Enhanced Osteoblast Differentiation and Inhibition of Adipogenesis of Human Mesenchymal Stem cells. J Bone Miner Res. 22:1720
  1. Diederichsen AC, Møller JE, Thayssen P, Junker AB, Videbaek L, Saekmose SG,

Barington T, Kristiansen M, Kassem M (2008) Effect of repeated intracoronary injection of bone marrow cells in patients with ischaemic heart failure the Danish stem cell study–congestive heart failure trial (DanCell-CHF). Eur J Heart Fail. 10:661

  1. Larsen KH, Frederiksen CM, Burns JS, Abdallah BM, Kassem M (2009). Identifying A Molecular Phenotype for Bone Marrow Stromal Cells With In Vivo Bone FormingCapacity. J Bone Miner Res. 25:796-808
  1. Saeed H, Abdallah BM, Ditzel N, Catala-Lehnen P, Qiu W, Amling M, Kassem M (2011).Telomerase-deficient mice exhibit bone loss due to defects in osteoblasts and increased osteoclastogenesis by inflammatory microenvironment. J Bone Miner Res. 26:1494-505
  2. Tormin A, Li O, Brune JC, Walsh S, Schütz B, Ehinger M, Ditzel N, Kassem M, Scheding S (2011). CD146 expression on primary non-hematopoietic bone marrow stem cells correlates to in situ localization. Blood. 117:5067-77
  1. Eskildsen T, Taipaleenmäki H, Stenvang J, Abdallah BM, Ditzel N, Nossent AY, Bak M, Kauppinen S, Kassem M (2011). MicroRNA-138 regulates osteogenic differentiation of human stromal (mesenchymal) stem cells in vivo. Proc Natl Acad Sci U S A. 108:6139-44.
  1. Jafari A, Siersbaek MS, Chen L, Qanie D, Zaher W, Abdallah BM, Kassem M. Pharmacological Inhibition of Protein Kinase G1 Enhances Bone Formation by Human Skeletal Stem Cells Through Activation of RhoA-Akt Signaling.

Stem Cells. 2015 Apr 8. doi: